LOXO-195, CAS [[1350884-56-8]]

Product Overview

• Article Name: LOXO-195, CAS [[1350884-56-8]]
• Biozol Catalog Number: BYT-ORB1298066
• Supplier Catalog Number: orb1298066
• Alternative Catalog Number: BYT-ORB1298066-1, BYT-ORB1298066-10, BYT-ORB1298066-2, BYT-ORB1298066-25, BYT-ORB1298066-5, BYT-ORB1298066-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Trk, Trk receptor, Trkreceptor, (6RS)-LOXO 195, (6RS)-LOXO195, (6RS)-LOXO-195, BAY 2731954, BAY2731954, BAY-2731954, LOXO 195, LOXO195, LOXO-195

Product Description

(6RS)-LOXO-195 (BAY 2731954) is a highly potent and selective inhibitor of the Trk family of tyrosine kinases. It is utilized in biochemical and cellular research to investigate Trk-driven oncogenesis and has demonstrated antitumor activity in preclinical in vivo models of NTRK-rearranged cancers.

Product Properties

• Molecular Weight: 380.42
• Purity: 99.54% (May vary between batches)
• CAS Number: [1350884-56-8]
• Formula: C20H21FN6O
• Target: Trk receptor

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.26 mM),DMSO:50 mg/mL (131.43 mM)