HM43239, CAS [[2294874-49-8]]

Product Overview

• Article Name: HM43239, CAS [[2294874-49-8]]
• Biozol Catalog Number: BYT-ORB1298100
• Supplier Catalog Number: orb1298100
• Alternative Catalog Number: BYT-ORB1298100-1, BYT-ORB1298100-1, BYT-ORB1298100-10, BYT-ORB1298100-100, BYT-ORB1298100-200, BYT-ORB1298100-25, BYT-ORB1298100-5, BYT-ORB1298100-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Tuspetinib, 2569527-64-4, HM43239, HM-43239, HM 43239, FLT3

Product Description

HM43239 is a potent, orally bioavailable, and selective Type I FLT3 inhibitor with low nM IC50 values against FLT3 WT, ITD, and D835Y mutants. It effectively blocks downstream signaling (p-STAT5, p-ERK) and inhibits proliferation while inducing apoptosis in leukemic cells in vitro, supporting its research application in acute myeloid leukemia (AML).

Product Properties

• Molecular Weight: 501.07
• Purity: 99.70% (May vary between batches)
• CAS Number: [2294874-49-8]
• Formula: C29H33ClN6
• Target: FLT,Apoptosis

Application Notes

• Application Notes: Solubility: DMSO:250 mg/mL (498.93 mM),10% DMSO+90% Corn Oil:2.5 mg/mL (4.99 mM)