Thalidomide 5-fluoride, CAS [[835616-61-0]]

Product Overview

• Article Name: Thalidomide 5-fluoride, CAS [[835616-61-0]]
• Biozol Catalog Number: BYT-ORB1298135
• Supplier Catalog Number: orb1298135
• Alternative Catalog Number: BYT-ORB1298135-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: E3 ligase-recruiting Moiety, Inhibitor, H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-, Ligand for E3 Ligase, Ligands for E3 Ligase, LigandforE3Ligase, inhibit, IRAK4 protein, protac, Thalidomide 5 fluoride, Thalidomide 5fluoride, Thalidomide 5-fluoride, Thalidomide

Product Description

Thalidomide 5-fluoride is a cereblon-binding ligand used to synthesize PROTAC IRAK4 degrader-1, a bifunctional molecule that targets the IRAK4 protein for degradation. This compound is a key component for developing proteolysis-targeting chimeras (PROTACs) applied in biochemical and cellular research to study IRAK4s role in oncology and immunology.

Product Properties

• Molecular Weight: 276.22
• Purity: 98.62% (May vary between batches)
• CAS Number: [835616-61-0]
• Formula: C13H9FN2O4
• Target: Apoptosis,Autophagy,Ligands for E3 Ligase

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (11.95 mM),DMSO:80 mg/mL (289.62 mM)