ASK1-IN-2, CAS [[2541792-70-3]]

Catalog Number: BYT-ORB1298138
Article Name: ASK1-IN-2, CAS [[2541792-70-3]]
Biozol Catalog Number: BYT-ORB1298138
Supplier Catalog Number: orb1298138
Alternative Catalog Number: BYT-ORB1298138-1, BYT-ORB1298138-1, BYT-ORB1298138-10, BYT-ORB1298138-100, BYT-ORB1298138-25, BYT-ORB1298138-5, BYT-ORB1298138-50
Manufacturer: Biorbyt
Category: Biochemikalien
Alternative Names: signal-regulating, ulcerative, inhibit, Inhibitor, MAP kinase kinase kinase, MEKK, MAPKKK, MAP3K, colitis, ASK1, ASK1 IN 2, ASK1IN2, ASK-1-IN-2, ASK1-IN-2, Apoptosis
ASK1-IN-2 is a potent, orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), demonstrating an IC50 of 32.8 nM. It has shown therapeutic potential in preclinical research for ulcerative colitis, with studies investigating its effects in both cellular assays and animal models of inflammatory disease.
Molecular Weight: 364.38
Purity: 99.36% (May vary between batches)
CAS Number: [2541792-70-3]
Formula: C19H17FN6O
Target: Apoptosis,ASK,MAPK
Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.72 mM),DMSO:249 mg/mL (683.35 mM)