Thalidomide-5-OH, CAS [[64567-60-8]]

Product Overview

• Article Name: Thalidomide-5-OH, CAS [[64567-60-8]]
• Biozol Catalog Number: BYT-ORB1298209
• Supplier Catalog Number: orb1298209
• Alternative Catalog Number: BYT-ORB1298209-500,BYT-ORB1298209-1
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: CRBN, E3 ligase-recruiting Moiety, 2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione, Ligands for E3 Ligase, LigandforE3Ligase, Ligand for E3 Ligase, inhibit, Inhibitor, PROTAC, Thalidomide, Thalidomide 5 OH, Thalidomide5OH, Thalidomide-5-OH

Product Description

Thalidomide-5-OH is a cereblon (CRBN)-binding ligand derived from thalidomide, used to construct PROTAC molecules for targeted protein degradation. This small molecule enables the study of CRBN-recruiting PROTACs in both cellular and in vivo models for probing disease-related protein functions.

Product Properties

• Molecular Weight: 274.23
• Purity: 98.94% (May vary between batches)
• CAS Number: [64567-60-8]
• Formula: C13H10N2O5
• Target: Apoptosis,Autophagy,Ligands for E3 Ligase

Application Notes

• Application Notes: Solubility: DMSO:60 mg/mL (218.79 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.29 mM)