JNJ-63576253, CAS [[2110428-64-1]]

Product Overview

• Article Name: JNJ-63576253, CAS [[2110428-64-1]]
• Biozol Catalog Number: BYT-ORB1298247
• Supplier Catalog Number: orb1298247
• Alternative Catalog Number: BYT-ORB1298247-1, BYT-ORB1298247-10, BYT-ORB1298247-100, BYT-ORB1298247-2, BYT-ORB1298247-25, BYT-ORB1298247-5, BYT-ORB1298247-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: CRPC, castration, cancer, androgen, Androgen Receptor, AndrogenReceptor, Inhibitor, JNJ 63576253, inhibit, JNJ63576253, JNJ-63576253, mutant, LNCaP, prostate, resistant, wild-type, TRC 253, TRC253, TRC-253

Product Description

JNJ-63576253 is a clinical-stage small molecule androgen receptor (AR) antagonist active against both wild-type and F877L-mutant forms, targeting castration-resistant prostate cancer (mCRPC). It is utilized in preclinical research to investigate AR signaling and resistance mechanisms in relevant in vitro and in vivo models.

Product Properties

• Molecular Weight: 538.97
• Purity: 99.27% (May vary between batches)
• CAS Number: [2110428-64-1]
• Formula: C23H22ClF3N6O2S
• Target: Androgen Receptor

Application Notes

• Application Notes: Solubility: H2O:insoluble,DMSO:200 mg/mL (371.08 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.28 mM)