NRX-252262, CAS [[2438637-61-5]]

Product Overview

• Article Name: NRX-252262, CAS [[2438637-61-5]]
• Biozol Catalog Number: BYT-ORB1298303
• Supplier Catalog Number: orb1298303
• Alternative Catalog Number: BYT-ORB1298303-1, BYT-ORB1298303-1, BYT-ORB1298303-10, BYT-ORB1298303-100, BYT-ORB1298303-25, BYT-ORB1298303-5, BYT-ORB1298303-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Beta catenin, betacatenin, beta-catenin, bcatenin, Inhibitor, inhibit, NRX252262, NRX-252262, NRX 252262, SCF(beta-TrCP)-E3 ligase, Wnt/beta-catenin, Wnt, Wnt/b-catenin, Wnt/betacatenin, betacatenin, beta-catenin

Product Description

NRX-252262 is a small molecule that potently enhances the interaction between beta-catenin and the SCFbeta-TrCP E3 ligase, leading to targeted degradation of mutant beta-catenin with an EC50 of 3.8 nM. It serves as a valuable chemical probe for studying Wnt/beta-catenin signaling in cancer research and has demonstrated proof-of-concept efficacy in cellular models of oncogenesis.

Product Properties

• Molecular Weight: 545.36
• Purity: 99.87% (May vary between batches)
• CAS Number: [2438637-61-5]
• Formula: C23H17Cl2F3N2O4S
• Target: Molecular Glues,Wnt/beta-catenin,E1/E2/E3 Enzyme

Application Notes

• Application Notes: Solubility: DMSO:8 mg/mL (14.67 mM)