NSC 617145 is a selective small molecule inhibitor of WRN helicase, specifically blocking its ATPase activity while sparing exonuclease function. This compound is a valuable research tool for studying WRNs role in DNA repair and genome stability in cellular and biochemical assays.
Molecular Weight:
400.04
Purity:
99.78% (May vary between batches)
CAS Number:
[203115-63-3]
Formula:
C13H10Cl4N2O4
Target:
DNA/RNA Synthesis
Application Notes:
Solubility: DMSO:6 mg/mL (15 mM)
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