oxLDL binding, inhibit, LOX-1, Inhibitor, BI 0115, BI0115, BI-0115, atherosclerosis
BI-0115 is a selective LOX-1 inhibitor that prevents oxLDL uptake by inducing tetramerization of the receptors ligand-binding domain, thereby blocking its function. This small molecule is a valuable research tool for studying atherosclerosis, endothelial dysfunction, and inflammation in both cellular and animal models.
Molecular Weight:
287.74
Purity:
99.69% (May vary between batches)
CAS Number:
[4929-23-1]
Formula:
C15H14ClN3O
Target:
Lipoxygenase
Application Notes:
Solubility: DMSO:2.88 mg/mL (10.01 mM)
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