Tuxobertinib (BDTX-189) is a highly selective, allosteric inhibitor targeting oncogenic mutations in EGFR and HER2, demonstrating potent anticancer activity. It has shown efficacy in preclinical in vitro and in vivo models for non-small cell lung cancer and other solid tumors driven by these mutations.
Molecular Weight:
561.03
Purity:
99.22% (May vary between batches)
CAS Number:
[2414572-47-5]
Formula:
C29H29ClN6O4
Target:
HER,RIP kinase,EGFR,BTK
Application Notes:
Solubility: DMSO:41.67 mg/mL (74.27 mM)
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