antiviral, inhibit, Nef, Human immunodeficiency virus, HIV, HIVProtease, HIV Protease, HIV 1 Nef IN 1, HIV-1 Nef, HIV1 NefIN1, HIV-1 Nef-IN-1, HIV-1, Inhibitor, PPI, SH3
HIV-1 Nef-IN-1 is a small molecule inhibitor that disrupts the HIV-1 Nef-SH3Hck protein-protein interaction with a Kd of 6.7 µM. This compound serves as a valuable research tool for studying Nef-mediated pathogenesis in vitro, including mechanisms of immune evasion and viral replication in cellular models.
Molecular Weight:
264.32
Purity:
99.90% (May vary between batches)
CAS Number:
[13728-56-8]
Formula:
C18H16O2
Target:
HIV Protease
Application Notes:
Solubility: DMSO:50 mg/mL (189.16 mM)
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