AEM1, CAS [[1030123-90-0]]

Product Overview

• Article Name: AEM1, CAS [[1030123-90-0]]
• Biozol Catalog Number: BYT-ORB1298474
• Supplier Catalog Number: orb1298474
• Alternative Catalog Number: BYT-ORB1298474-1, BYT-ORB1298474-10, BYT-ORB1298474-100, BYT-ORB1298474-2, BYT-ORB1298474-25, BYT-ORB1298474-5, BYT-ORB1298474-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: AEM 1, AEM1, AEM-1, Inhibitor, NRF2, Keap1-Nrf2, inhibit

Product Description

AEM1 is a small molecule inhibitor that suppresses oncogenic NRF2 signaling. It downregulates NRF2 target genes, enhancing chemosensitivity in A549 lung cancer cells and impeding tumor growth in both cell culture and animal models, supporting its use in cancer therapeutics research.

Product Properties

• Molecular Weight: 379.41
• Purity: 99.88% (May vary between batches)
• CAS Number: [1030123-90-0]
• Formula: C20H14FN3O2S
• Target: Nrf2

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.27 mM),DMSO:30 mg/mL (79.07 mM)