OV935, OV-935, OV 935, NMDA, inhibit, Inhibitor, epilepsy, cholesterol, CYPs, CYP46A1, Cytochrome P450, 24-hydroxylase, antiepileptic, Soticlestat, TAK935, TAK-935, TAK 935
Soticlestat (OV935) is a potent, selective, and orally bioavailable inhibitor of cholesterol 24-hydroxylase (CYP46A1). It is a research compound for investigating epilepsy syndromes, with studies demonstrating activity in both in vitro enzymatic assays and in vivo rodent seizure models.