Flumatinib mesylate, CAS [[895519-91-2]]

Product Overview

• Article Name: Flumatinib mesylate, CAS [[895519-91-2]]
• Biozol Catalog Number: BYT-ORB1299437
• Supplier Catalog Number: orb1299437
• Alternative Catalog Number: BYT-ORB1299437-1,BYT-ORB1299437-5,BYT-ORB1299437-10,BYT-ORB1299437-25,BYT-ORB1299437-50,BYT-ORB1299437-100,BYT-ORB1299437-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: CD117, cKit, c-Kit, c-Abl, BcrAbl, Bcr-Abl, inhibit, Platelet-derived growth factor receptor, Flumatinib, Flumatinib Mesylate, Flumatinib mesylate, Inhibitor, HHGV 678, HHGV 678 Mesylate, HHGV678, HHGV-678, HHGV678 mesylate, HHGV678 Mesylate, HHGV-678 Mesylate, SCFR, PDGFR, PDGFRbeta

Product Description

Flumatinib mesylate is a potent and selective small molecule inhibitor targeting c-Abl, PDGFRbeta, and c-Kit tyrosine kinases. It has demonstrated efficacy in overcoming resistance conferred by specific KIT mutations in preclinical studies, supporting its investigation in related hematological and solid tumor research both in vitro and in vivo.

Product Properties

• Molecular Weight: 658.69
• Purity: 99.82% (May vary between batches)
• CAS Number: [895519-91-2]
• Formula: C30H33F3N8O4S
• Target: PDGFR,Bcr-Abl,c-Kit

Application Notes

• Application Notes: Solubility: DMSO:70 mg/mL (106.27 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.04 mM),H2O:50 mg/mL (75.91 mM)