CU-CPT9b, CAS [[2162962-69-6]]

Product Overview

• Article Name: CU-CPT9b, CAS [[2162962-69-6]]
• Biozol Catalog Number: BYT-ORB1299939
• Supplier Catalog Number: orb1299939
• Alternative Catalog Number: BYT-ORB1299939-1, BYT-ORB1299939-1, BYT-ORB1299939-10, BYT-ORB1299939-100, BYT-ORB1299939-200, BYT-ORB1299939-25, BYT-ORB1299939-5, BYT-ORB1299939-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: CUCPT9b, CU-CPT9b, CU-CPT-9b, CU CPT9b, Inhibitor, inhibit, TLR8-specific antagonist 1, TLR8, TLR, Toll-like Receptor (TLR)

Product Description

CU-CPT9b is a potent and selective TLR8 antagonist with a Kd of 21 nM. It inhibits R-848-induced NF-kappaB activation in TLR8-overexpressing HEK-Blue cells with an IC50 of 0.7 nM. This tool compound is valuable for in vitro studies investigating TLR8 signaling and its role in autoimmune, inflammatory, and antiviral research.

Product Properties

• Molecular Weight: 251.28
• Purity: 98.10% (May vary between batches)
• CAS Number: [2162962-69-6]
• Formula: C16H13NO2
• Target: TLR

Application Notes

• Application Notes: Solubility: DMSO:100 mg/mL (397.96 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.92 mM)