BDP5290, BDP-5290, BDP 5290, inhibit, Inhibitor, Rho-kinase, Rho-associated kinase, Rho-associated protein kinase, ROCK, ROK
BDP5290 is a potent dual ROCK and MRCK inhibitor, exhibiting IC50 values of 5 nM (ROCK1), 50 nM (ROCK2), 10 nM (MRCKa), and 100 nM (MRCKB). This small molecule is a valuable research tool for studying cytoskeletal dynamics, cell motility, and contractility in both cellular and animal models of cancer and fibrosis.
Molecular Weight:
371.82
Purity:
98.00% (May vary between batches)
CAS Number:
[1817698-21-7]
Formula:
C17H18ClN7O
Target:
ROCK
Application Notes:
Solubility: DMSO:12.5 mg/mL (33.62 mM)
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