THZ2, CAS [[1604810-84-5]]

Product Overview

• Article Name: THZ2, CAS [[1604810-84-5]]
• Biozol Catalog Number: BYT-ORB1299945
• Supplier Catalog Number: orb1299945
• Alternative Catalog Number: BYT-ORB1299945-1, BYT-ORB1299945-1, BYT-ORB1299945-10, BYT-ORB1299945-100, BYT-ORB1299945-25, BYT-ORB1299945-5, BYT-ORB1299945-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Inhibitor, inhibit, Cyclin dependent kinase, CDK7-IN-1, CDK, THZ2, THZ-2, THZ 2

Product Description

THZ2 (CDK7-IN-1) is a potent and selective CDK7 inhibitor derived from THZ1, exhibiting an IC50 of 13.9 nM. It is a research tool for investigating CDK7s role in transcription and cell cycle progression, with studies demonstrating its potential efficacy in models of triple-negative breast cancer (TNBC) both in vitro and in vivo.

Product Properties

• Molecular Weight: 566.05
• Purity: 98.28% (May vary between batches)
• CAS Number: [1604810-84-5]
• Formula: C31H28ClN7O2
• Target: CDK

Application Notes

• Application Notes: Solubility: DMSO:39 mg/mL (68.9 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.53 mM)