Motolimod, CAS [[926927-61-9]]

Product Overview

• Article Name: Motolimod, CAS [[926927-61-9]]
• Biozol Catalog Number: BYT-ORB1300365
• Supplier Catalog Number: orb1300365
• Alternative Catalog Number: BYT-ORB1300365-1,BYT-ORB1300365-5,BYT-ORB1300365-10,BYT-ORB1300365-25,BYT-ORB1300365-50,BYT-ORB1300365-100
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: inhibit, Motolimod, Inhibitor, TLR8, TLR, Toll-like Receptor (TLR), VTX2337, VTX-2337, VTX378, VTX-378, VTX 2337, VTX 378

Product Description

Motolimod (VTX-378/VTX-2337) is a potent and selective small molecule agonist of Toll-like receptor 8 (TLR8), exhibiting an EC50 of 100 nM and over 50-fold selectivity against TLR7. It is utilized in immunological research to study innate immune activation and has been investigated in preclinical models for its potential in cancer immunotherapy and as a vaccine adjuvant.

Product Properties

• Molecular Weight: 458.6
• Purity: 99.66% (May vary between batches)
• CAS Number: [926927-61-9]
• Formula: C28H34N4O2
• Target: TLR

Application Notes

• Application Notes: Solubility: Ethanol:12 mg/mL (26.17 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),DMSO:51 mg/mL (111.21 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.36 mM)