Monomethyl auristatin E, CAS [[474645-27-7]]

Product Overview

• Article Name: Monomethyl auristatin E, CAS [[474645-27-7]]
• Biozol Catalog Number: BYT-ORB1300366
• Supplier Catalog Number: orb1300366
• Alternative Catalog Number: BYT-ORB1300366-10,BYT-ORB1300366-25,BYT-ORB1300366-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Microtubule Associated, microtubule, MicrotubuleAssociated, Microtubule/Tubulin, MMAE, inhibit, Inhibitor, Monomethyl auristatin E, ADCCytotoxin, ADC Cytotoxin, ADC Payload, Apoptosis, SGD 1010, SGD1010, SGD-1010, Vedotin

Product Description

Monomethyl auristatin E (MMAE) is a potent tubulin polymerization inhibitor that disrupts cell division. It serves as the cytotoxic payload in numerous antibody-drug conjugates (ADCs) and is widely used in oncology research for both in vitro cytotoxicity studies and in vivo xenograft models.

Product Properties

• Molecular Weight: 717.98
• Purity: 99.90% (May vary between batches)
• CAS Number: [474645-27-7]
• Formula: C39H67N5O7
• Target: Apoptosis,ADC Cytotoxin,Microtubule Associated

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.79 mM),DMSO:71.8 mg/mL (100 mM)