EAI045, CAS [[1942114-09-1]]

Product Overview

• Article Name: EAI045, CAS [[1942114-09-1]]
• Biozol Catalog Number: BYT-ORB1300432
• Supplier Catalog Number: orb1300432
• Alternative Catalog Number: BYT-ORB1300432-5,BYT-ORB1300432-1,BYT-ORB1300432-10,BYT-ORB1300432-25,BYT-ORB1300432-50,BYT-ORB1300432-100
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: EAI 045, EAI045, EAI-045, HER1, EGFR, EGFR mutants, ErbB-1, Epidermal growth factor receptor, inhibit, Inhibitor

Product Description

EAI045 is a selective allosteric inhibitor that potently targets drug-resistant EGFR mutants while sparing the wild-type receptor. It is a valuable chemical probe for studying resistance mechanisms in non-small cell lung cancer (NSCLC) and has demonstrated efficacy in both cellular assays and in vivo models.

Product Properties

• Molecular Weight: 383.4
• Purity: 99.73% (May vary between batches)
• CAS Number: [1942114-09-1]
• Formula: C19H14FN3O3S
• Target: EGFR

Application Notes

• Application Notes: Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble),DMSO:16.67 mg/mL (43.48 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.22 mM)