E3330, CAS [[136164-66-4]]

Product Overview

• Article Name: E3330, CAS [[136164-66-4]]
• Biozol Catalog Number: BYT-ORB1300433
• Supplier Catalog Number: orb1300433
• Alternative Catalog Number: BYT-ORB1300433-1, BYT-ORB1300433-1, BYT-ORB1300433-5, BYT-ORB1300433-10, BYT-ORB1300433-25, BYT-ORB1300433-50, BYT-ORB1300433-100
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Activator Protein 1, anticancer, APE1, APE1(Ref-1), AP-1, APX3330, APX-3330, APX 3330, DNASynthesis, E 3330, DNA-binding, DNA/RNA Synthesis, DNA Synthesis, HIF, HIFProlylHydroxylase, HIFs, HIF-PH, HIF/HIFProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF ProlylHydroxylase, HIF/HIF ProlylHydroxylase, HIF/HIF Prolyl-Hydroxylase, Hypoxia-inducible factors, HUVECs, E3330, E-3330, endonuclease, EPCs, H1975, NSCLC cells, Nuclear factor-kappaB, Nuclear factor-kappaB, NF-kappaB, orally, neuroprotective, pancreatic cancer, PANC1, PCECs, Inhibitor, inhibit, IL-8, VEGFR, Vascular endothelial growth factor receptor, Reactive Oxygen Species, REF-1, RNA Synthesis, RNASynthesis, TNF-alpha

Product Description

E3330 is a potent and selective small molecule inhibitor of the APE1/Ref-1 protein. By targeting APE1s redox function, it effectively suppresses NF-kappaB DNA-binding activity. This inhibitor is a valuable research tool for studying oxidative stress signaling, inflammation, and cancer biology in both cellular and animal models.

Product Properties

• Molecular Weight: 378.46
• Purity: 99.52% (May vary between batches)
• CAS Number: [136164-66-4]
• Formula: C21H30O6
• Target: DNA/RNA Synthesis,HIF/HIF Prolyl-Hydroxylase,Reactive Oxygen Species,ROS,VEGFR,NF-kappaB

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.28 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),Ethanol:70 mg/mL (184.96 mM),DMSO:50 mg/mL (132.11 mM)