CB-5083, CAS [[1542705-92-9]]

Product Overview

• Article Name: CB-5083, CAS [[1542705-92-9]]
• Biozol Catalog Number: BYT-ORB1300457
• Supplier Catalog Number: orb1300457
• Alternative Catalog Number: BYT-ORB1300457-1,BYT-ORB1300457-2,BYT-ORB1300457-5,BYT-ORB1300457-10,BYT-ORB1300457-25,BYT-ORB1300457-50,BYT-ORB1300457-100,BYT-ORB1300457-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Cdc48, CB5083, CB-5083, CB 5083, ATPase, AAA, p97, Inhibitor, inhibit, multiple, myeloma, VCP, tumors, solid

Product Description

CB-5083 is a potent, selective, and orally available inhibitor of the p97 AAA ATPase, with an IC50 of 11 nM. It is widely used in cancer research to study protein homeostasis and has demonstrated antitumor activity in both cellular assays and in vivo xenograft models.

Product Properties

• Molecular Weight: 413.47
• Purity: >99.99% (May vary between batches)
• CAS Number: [1542705-92-9]
• Formula: C24H23N5O2
• Target: p97

Application Notes

• Application Notes: Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble),Ethanol:11 mg/mL (26.6 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:6 mg/mL (14.51 mM),DMSO:247.5 mg/mL (598.59 mM)