Bafilomycin A1, CAS [[88899-55-2]]

Product Overview

• Article Name: Bafilomycin A1, CAS [[88899-55-2]]
• Biozol Catalog Number: BYT-ORB1300510
• Supplier Catalog Number: orb1300510
• Alternative Catalog Number: BYT-ORB1300510-160, BYT-ORB1300510-500, BYT-ORB1300510-1, BYT-ORB1300510-5, BYT-ORB1300510-10
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Antibiotic, Antibacterial, Apoptosis, apoptosis, Autophagy, autophagy, Bacterial, Baf A1, Bafilomycin A 1, Bafilomycin A1, Bafilomycin A-1, BafA 1, BafA1, BafA-1, Inhibitor, inhibit, Protonpump, Proton pump, Proton Pump

Product Description

Bafilomycin A1 is a specific and reversible macrolide antibiotic that potently inhibits V-ATPase (IC50=0.44 nM). It blocks autophagosome-lysosome fusion, arresting late-stage autophagy, and can induce apoptosis, making it a valuable tool for studying autophagy, cancer, and neurodegeneration in cellular and animal models.

Product Properties

• Molecular Weight: 622.83
• Purity: 99.36% (May vary between batches)
• CAS Number: [88899-55-2]
• Formula: C35H58O9
• Target: Apoptosis,Autophagy,Antibacterial,Antibiotic,Proton pump

Application Notes

• Application Notes: Solubility: DMSO:99 mg/mL (158.95 mM),5% DMSO+40% PEG300+5% Tween 80+50% Saline:0.3 mg/mL (0.48 mM),H2O:< 0.1 mg/mL (insoluble)