WYE-354, CAS [[1062169-56-5]]

Product Overview

• Article Name: WYE-354, CAS [[1062169-56-5]]
• Biozol Catalog Number: BYT-ORB1300518
• Supplier Catalog Number: orb1300518
• Alternative Catalog Number: BYT-ORB1300518-1,BYT-ORB1300518-5,BYT-ORB1300518-10,BYT-ORB1300518-25,BYT-ORB1300518-50,BYT-ORB1300518-100
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Autophagy, Apoptosis, inhibit, mTOR, Inhibitor, Mammalian target of Rapamycin, WYE 354, WYE-354, PI3Kalpha, WYE354, PI3Kgamma

Product Description

WYE-354 is a potent, selective, and ATP-competitive mTOR inhibitor with an IC50 of 5 nM. It effectively suppresses mTORC2-mediated P-AKT(S473) and mTORC1-mediated P-S6K(T389) signaling, demonstrating high selectivity over PI3K isoforms. This inhibitor is a valuable tool for investigating mTOR pathway biology in both cellular and in vivo cancer research models.

Product Properties

• Molecular Weight: 495.53
• Purity: 99.61% (May vary between batches)
• CAS Number: [1062169-56-5]
• Formula: C24H29N7O5
• Target: Autophagy,mTOR,PI3K,Apoptosis

Application Notes

• Application Notes: Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble),DMSO:92 mg/mL (185.66 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.02 mM)