Tiotropium Bromide hydrate is a potent, long-acting muscarinic antagonist developed for COPD research. It exhibits high affinity for M1, M2, and M3 receptor subtypes, with kinetic selectivity due to slow dissociation from M1/M3 receptors. Its application extends to in vitro binding assays and in vivo studies of airway smooth muscle contraction and cholinergic neurotransmission.
Molecular Weight:
490.43
Purity:
99.41% (May vary between batches)
CAS Number:
[411207-31-3]
Formula:
C19H24BrNO5S2
Target:
AChR
Application Notes:
Solubility: PBS:10 mg/mL (20.39 mM),DMSO:65 mg/mL (132.54 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),Ethanol:< 1 mg/mL (insoluble or slightly soluble)
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