SKI II, CAS [[312636-16-1]]

Product Overview

• Article Name: SKI II, CAS [[312636-16-1]]
• Biozol Catalog Number: BYT-ORB1300568
• Supplier Catalog Number: orb1300568
• Alternative Catalog Number: BYT-ORB1300568-10,BYT-ORB1300568-25,BYT-ORB1300568-50,BYT-ORB1300568-100,BYT-ORB1300568-200
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: S1PReceptor, S1P Receptor, SKI II, Sphingosine kinase, SphK-I2, SphK1, SphK, Wnt/b-catenin, Wnt, Wnt/beta-catenin, Wnt/betacatenin, betacatenin, inhibit, Inhibitor, beta-catenin, betacatenin, bcatenin, Apoptosis

Product Description

SKI-II is a potent and selective non-ATP-competitive inhibitor of sphingosine kinase 1 (SphK1) with an IC50 of 0.5 µM, showing no activity against PKCalpha, PI3K, or ERK2. This tool compound is widely used in vitro and in vivo to investigate the S1P signaling pathway in cancer, inflammation, and angiogenesis research.

Product Properties

• Molecular Weight: 302.78
• Purity: 99.97% (May vary between batches)
• CAS Number: [312636-16-1]
• Formula: C15H11ClN2OS
• Target: Wnt/beta-catenin,S1P Receptor,Apoptosis

Application Notes

• Application Notes: Solubility: DMSO:40 mg/mL (132.11 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.61 mM)