SB 415286, CAS [[264218-23-7]]

Product Overview

• Article Name: SB 415286, CAS [[264218-23-7]]
• Biozol Catalog Number: BYT-ORB1300580
• Supplier Catalog Number: orb1300580
• Alternative Catalog Number: BYT-ORB1300580-1,BYT-ORB1300580-10,BYT-ORB1300580-100,BYT-ORB1300580-25,BYT-ORB1300580-5,BYT-ORB1300580-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: GSK-3alpha/beta, GSK-3, GSK3, Glycogen synthase kinase-3, Glycogen synthase kinase 3, Inhibitor, inhibit, Apoptosis, SB 415286, SB415286, SB-415286

Product Description

SB 415286 is a potent and selective ATP-competitive inhibitor of glycogen synthase kinase-3 (GSK-3), exhibiting IC50 values of 78 nM and 31 nM for GSK-3alpha and GSK-3beta, respectively. This cell-permeable compound is widely used in vitro and in vivo to investigate GSK-3s role in Wnt/beta-catenin signaling, neurodegenerative diseases, and glucose metabolism.

Product Properties

• Molecular Weight: 359.72
• Purity: 99.56% (May vary between batches)
• CAS Number: [264218-23-7]
• Formula: C16H10ClN3O5
• Target: GSK-3,Apoptosis

Application Notes

• Application Notes: Solubility: DMSO:18 mg/mL (50.04 mM),Ethanol:9 mg/mL (25.02 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.56 mM)