Ro 31-8220 Mesylate, CAS [[138489-18-6]]

Catalog Number: BYT-ORB1300591
Article Name: Ro 31-8220 Mesylate, CAS [[138489-18-6]]
Biozol Catalog Number: BYT-ORB1300591
Supplier Catalog Number: orb1300591
Alternative Catalog Number: BYT-ORB1300591-1,BYT-ORB1300591-10,BYT-ORB1300591-100,BYT-ORB1300591-2,BYT-ORB1300591-25,BYT-ORB1300591-5,BYT-ORB1300591-50
Manufacturer: Biorbyt
Category: Biochemikalien
Alternative Names: Bisindolylmaleimide IX mesylate, Ro 31-8220, Ro 318220 Mesylate, Ro 31-8220 Mesylate, Ro 31-8220 methanesulfonate, Ro 31 8220 Mesylate, Protein kinase C, PKCalpha, PKCbeta1, PKCbeta2, PKCgamma, PKCepsilon, PKC
Ro 31-8220 Mesylate is a potent, cell-permeable pan-PKC inhibitor targeting isoforms alpha, betaI, betaII, gamma, and epsilon. It also effectively inhibits kinases MSK1, MAPKAP-K1b, S6K1, and GSK3beta. This compound is widely used in vitro and in vivo to investigate PKC-mediated signaling pathways in cancer, neuroscience, and inflammation research.
Molecular Weight: 553.65
Purity: 99.18% (May vary between batches)
CAS Number: [138489-18-6]
Formula: C25H23N5O2SCH4O3S
Target: JNK,PKC
Application Notes: Solubility: DMSO:55.4 mg/mL (100.06 mM),Ethanol:2.8 mg/mL (5.06 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.61 mM)