Raltitrexed, CAS [[112887-68-0]]
Catalog Number:
BYT-ORB1300600
Product Overview
Article Name:
Raltitrexed, CAS [[112887-68-0]]
Biozol Catalog Number:
BYT-ORB1300600
Supplier Catalog Number:
orb1300600
Alternative Catalog Number:
BYT-ORB1300600-1,BYT-ORB1300600-10,BYT-ORB1300600-100,BYT-ORB1300600-200,BYT-ORB1300600-25,BYT-ORB1300600-5,BYT-ORB1300600-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
inhibit, Nucleoside Antimetabolite, NucleosideAntimetabolite, Nucleoside Antimetabolite/Analog, Inhibitor, ICI-D 1694, ICI-D1694, ICI-D-1694, Analog, DNASynthesis, DNA Synthesis, D 1694, D1694, D-1694, Thymidylate Synthase, Thymidylate synthase, Raltitrexed, ZD 1694, ZD1694, ZD-1694, Tomudex, RNA Synthesis, RNASynthesis
Product Description
Raltitrexed (D1694) is a potent thymidylate synthase inhibitor with an IC50 of 9 nM, effectively suppressing L1210 leukemia cell growth in vitro. It is widely used in cancer research, including studies on colorectal carcinoma, both in cellular assays and in vivo models.
Product Properties
Molecular Weight:
458.49
Purity:
99.29% (May vary between batches)
CAS Number:
[112887-68-0]
Formula:
C21H22N4O6S
Target:
Nucleoside Antimetabolite/Analog,DNA/RNA Synthesis
Application Notes
Application Notes:
Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.72 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),Ethanol:< 1 mg/mL (insoluble or slightly soluble),DMSO:123 mg/mL (268.27 mM)