NU6027, CAS [[220036-08-8]]
Catalog Number:
BYT-ORB1300616
Product Overview
Article Name:
NU6027, CAS [[220036-08-8]]
Biozol Catalog Number:
BYT-ORB1300616
Supplier Catalog Number:
orb1300616
Alternative Catalog Number:
BYT-ORB1300616-10, BYT-ORB1300616-100, BYT-ORB1300616-200, BYT-ORB1300616-25, BYT-ORB1300616-5, BYT-ORB1300616-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
DNAPK, DNA-PK, Cyclin dependent kinase, cytotoxicity, CDK1, CDK, CDK2, cisplatin, cancer, Ataxia telangiectasia mutated, ATM, ATM/ATR, ATM and RAD3 related, ATR, NU 6027, NU6027, NU-6027, inhibit, Inhibitor, hydroxyurea
Product Description
NU6027 is a cell-permeable small molecule inhibitor targeting key DNA damage response kinases, with Ki values of 0.4 µM for ATR, 2.5 µM/1.3 µM for CDK1/2, and 2.2 µM for DNA-PK. It is a valuable research tool for studying cell cycle checkpoints and DNA repair mechanisms in both in vitro and in vivo cancer models.
Product Properties
Molecular Weight:
251.29
Purity:
99.85% (May vary between batches)
CAS Number:
[220036-08-8]
Formula:
C11H17N5O2
Target:
ATM/ATR,DNA-PK,CDK
Application Notes
Application Notes:
Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.98 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),Ethanol:3 mg/mL (11.94 mM),DMSO:5.5 mg/mL (21.89 mM)
