ME0328, CAS [[1445251-22-8]]

Product Overview

• Article Name: ME0328, CAS [[1445251-22-8]]
• Biozol Catalog Number: BYT-ORB1300642
• Supplier Catalog Number: orb1300642
• Alternative Catalog Number: BYT-ORB1300642-1, BYT-ORB1300642-10, BYT-ORB1300642-100, BYT-ORB1300642-200, BYT-ORB1300642-25, BYT-ORB1300642-5, BYT-ORB1300642-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: PARP, PARP3, PARP1, inhibit, Inhibitor, ME0328, ME-0328, ME 0328, poly ADP ribose polymerase

Product Description

ME0328 is a potent small molecule inhibitor exhibiting high selectivity for PARP3, with an IC50 of 0.89 µM and approximately 7-fold selectivity over PARP1. This compound is a valuable chemical probe for investigating PARP3-specific functions in DNA repair pathways, supporting both in vitro biochemical assays and cellular mechanism-of-action studies.

Product Properties

• Molecular Weight: 321.37
• Purity: 99.84% (May vary between batches)
• CAS Number: [1445251-22-8]
• Formula: C19H19N3O2
• Target: PARP

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.22 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),DMSO:60 mg/mL (186.7 mM),Ethanol:< 1 mg/mL (insoluble or slightly soluble)