KU0060648, KU-0060648, KU 0060648, inhibit, mTOR, Inhibitor, Mammalian target of Rapamycin, DNA-dependent protein kinase, DNAPK, DNA-PK, PI3K, PI3Kalpha, PI3Kbeta, PI3Kgamma, PI3Kdelta, Phosphoinositide 3-kinase
KU-0060648 is a potent small molecule inhibitor that primarily targets DNA-PK and the PI3Kalpha, beta, and delta isoforms with low nanomolar IC50 values, while showing significantly weaker activity against PI3Kgamma. This profile makes it a useful research tool for investigating DNA damage response and PI3K signaling pathways in both cellular and animal models of cancer and other diseases.
Molecular Weight:
582.71
Purity:
99.21% (May vary between batches)
CAS Number:
[881375-00-4]
Formula:
C33H34N4O4S
Target:
PI3K,mTOR,DNA-PK
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