Indoximod, CAS [[110117-83-4]]

Catalog Number: BYT-ORB1300675
Article Name: Indoximod, CAS [[110117-83-4]]
Biozol Catalog Number: BYT-ORB1300675
Supplier Catalog Number: orb1300675
Alternative Catalog Number: BYT-ORB1300675-1, BYT-ORB1300675-2, BYT-ORB1300675-200, BYT-ORB1300675-500
Manufacturer: Biorbyt
Category: Biochemikalien
Alternative Names: tryptophan, Trp mimetic, Inhibitor, IDO, NLG 8189, NLG8189, NLG-8189, mTORC1, Indoleamine 2,3-Dioxygenase, Indoleamine 2,3Dioxygenase (IDO), Indoleamine 2,3-Dioxygenase (IDO), Indoleamine2,3Dioxygenase, Indoleamine2,3Dioxygenase(IDO), Indoximod, Indoximod (NLG-8189), immunotherapeutic vaccines, inhibit, cancer, 1-Methyl-D-tryptophan
Indoximod (NLG-8189) is a methylated tryptophan analog that acts as an immune checkpoint inhibitor by targeting indoleamine 2,3-dioxygenase (IDO). Its inhibition of IDO prevents tryptophan depletion, thereby countering T-cell anergy and immunosuppression. This small molecule is utilized in both in vitro and in vivo research to study cancer immunotherapy, autoimmune diseases, and T-cell function.
Molecular Weight: 218.25
Purity: 99.55% (May vary between batches)
CAS Number: [110117-83-4]
Formula: C12H14N2O2
Target: Indoleamine 2,3-Dioxygenase (IDO),IDO
Application Notes: Solubility: DMSO:Slightly soluble