Vactosertib, CAS [[1352608-82-2]]

Product Overview

• Article Name: Vactosertib, CAS [[1352608-82-2]]
• Biozol Catalog Number: BYT-ORB1300718
• Supplier Catalog Number: orb1300718
• Alternative Catalog Number: BYT-ORB1300718-1, BYT-ORB1300718-1, BYT-ORB1300718-10, BYT-ORB1300718-100, BYT-ORB1300718-25, BYT-ORB1300718-5, BYT-ORB1300718-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Vactosertib, Transforming growth factor beta receptors, Smad, TEW 7197, TEW7197, TEW-7197, TGF-b/Smad, TGFbeta, TGFb, TGF-beta Receptor, TGF-beta/Smad, TGFbeta, TGF-beta, TGFbeta/Smad, survival, p38alpha, Inhibitor, EW7197, EW-7197, EW 7197, inhibit, invasion, migration, antimetastatic, cancer, ALK5, ALK3, ALK4, ALK2, ALK1, breast, cell

Product Description

Vactosertib (EW-7197) is an orally active, small-molecule inhibitor targeting the TGF-beta receptor type I (ALK5). It is widely used in cancer research to investigate TGF-beta signaling pathways in both in vitro cellular assays and in vivo animal models for its potential antitumor effects.

Product Properties

• Molecular Weight: 399.42
• Purity: 99.81% (May vary between batches)
• CAS Number: [1352608-82-2]
• Formula: C22H18FN7
• Target: ALK,TGF-beta/Smad

Application Notes

• Application Notes: Solubility: DMSO:252.5 mg/mL (632.17 mM),Ethanol:40 mg/mL (100.15 mM),H2O:< 1 mg/mL (insoluble or slightly soluble)