Droxinostat, CAS [[99873-43-5]]

Product Overview

• Article Name: Droxinostat, CAS [[99873-43-5]]
• Biozol Catalog Number: BYT-ORB1300731
• Supplier Catalog Number: orb1300731
• Alternative Catalog Number: BYT-ORB1300731-1, BYT-ORB1300731-100, BYT-ORB1300731-200, BYT-ORB1300731-25, BYT-ORB1300731-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Droxinostat, cancer, Apoptosis, NS41080, NS-41080, NS 41080, inhibit, Inhibitor, hepatocellular carcinoma (HCC), HDAC9, HDAC8, HDAC3, HDAC6, HDAC, HDAC10, histone deacetylase (HDAC), Histone deacetylases

Product Description

Droxinostat is a selective histone deacetylase (HDAC) inhibitor, primarily targeting HDAC6 and HDAC8 with IC50 values of 2.47 µM and 1.46 µM, respectively. It demonstrates over 8-fold selectivity against HDAC3 and shows no activity against several other HDAC isoforms. This compound is a valuable research tool for studying epigenetic mechanisms in both cellular and animal models of cancer and neurological diseases.

Product Properties

• Molecular Weight: 243.69
• Purity: 99.83% (May vary between batches)
• CAS Number: [99873-43-5]
• Formula: C11H14ClNO3
• Target: Apoptosis,HDAC

Application Notes

• Application Notes: Solubility: DMSO:46 mg/mL (188.76 mM),Ethanol:46 mg/mL (188.76 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.21 mM),H2O:< 1 mg/mL (insoluble or slightly soluble)