CYC-116, CAS [[693228-63-6]]

Product Overview

• Article Name: CYC-116, CAS [[693228-63-6]]
• Biozol Catalog Number: BYT-ORB1300751
• Supplier Catalog Number: orb1300751
• Alternative Catalog Number: BYT-ORB1300751-10, BYT-ORB1300751-100, BYT-ORB1300751-200, BYT-ORB1300751-25, BYT-ORB1300751-5, BYT-ORB1300751-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: AuroraKinase, Aurora Kinase, Aurora B, Aurora A, CYC 116, CYC116, CYC-116, CDK2/CyclinE, CDK9/CyclinT, p70 S6K, Inhibitor, inhibit, FLT3, S6Kinase, S6 Kinase, VEGFR2

Product Description

CYC116 is a potent, selective dual Aurora A/B kinase inhibitor (Ki = 8.0/9.2 nM) with weaker activity against VEGFR2 and minimal off-target effects on other key kinases. It has been utilized in preclinical research to investigate cell cycle disruption and antitumor efficacy in both cellular and animal models.

Product Properties

• Molecular Weight: 368.46
• Purity: 97.59% (May vary between batches)
• CAS Number: [693228-63-6]
• Formula: C18H20N6OS
• Target: S6 Kinase,CDK,Aurora Kinase,FLT,VEGFR

Application Notes

• Application Notes: Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble),DMSO:13.4 mg/mL (36.37 mM),Ethanol:< 1 mg/mL (insoluble or slightly soluble)