Butein, CAS [[487-52-5]]

Product Overview

• Article Name: Butein, CAS [[487-52-5]]
• Biozol Catalog Number: BYT-ORB1300778
• Supplier Catalog Number: orb1300778
• Alternative Catalog Number: BYT-ORB1300778-1, BYT-ORB1300778-1, BYT-ORB1300778-10, BYT-ORB1300778-100, BYT-ORB1300778-2, BYT-ORB1300778-25, BYT-ORB1300778-5, BYT-ORB1300778-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: cell, Apoptosis, Autophagy, Butein, AKT, 2,3,4,4-tetrahydroxy Chalcone, EGFR, Epidermal growth factor receptor, ErbB-1, ERK, FoxO3a, HER1, HepG2, HeLa, MAPK, PDE4, p60c-src, inhibit, Inhibitor, Phosphodiesterase (PDE), phosphodiesterase, PKB, SIRT1, p38

Product Description

Butein is a multi-target small molecule that acts as a cAMP-specific PDE inhibitor, a protein tyrosine kinase inhibitor, and a SIRT1 activator. Research indicates it can sensitize HeLa cells to Cisplatin-induced cytotoxicity by modulating FoxO3a through the AKT and ERK/p38 MAPK signaling pathways, highlighting its utility in cancer research.

Product Properties

• Molecular Weight: 272.25
• Purity: >99.99% (May vary between batches)
• CAS Number: [487-52-5]
• Formula: C15H12O5
• Target: Apoptosis,PDE,Autophagy,EGFR

Application Notes

• Application Notes: Solubility: 10% DMSO+90% Saline:2.5 mg/mL (9.18 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),Ethanol:51 mg/mL (187.33 mM),DMSO:237.5 mg/mL (872.36 mM)