Buclizine dihydrochloride is a histamine H1 receptor antagonist used in research for its antiemetic and antivertigo properties. It acts by blocking central muscarinic and histamine receptors, inhibiting the chemoreceptor trigger zone. This compound is applied in neuropharmacology studies investigating nausea, vomiting, and vestibular function in experimental models.
Molecular Weight:
505.95
Purity:
99.56% (May vary between batches)
CAS Number:
[129-74-8]
Formula:
C28H33ClN22HCl
Target:
5-HT Receptor,AChR,Histamine Receptor
Application Notes:
Solubility: DMSO:11 mg/mL (21.74 mM)
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