PD318088, CAS [[391210-00-7]]

Product Overview

• Article Name: PD318088, CAS [[391210-00-7]]
• Biozol Catalog Number: BYT-ORB1301030
• Supplier Catalog Number: orb1301030
• Alternative Catalog Number: BYT-ORB1301030-1,BYT-ORB1301030-5,BYT-ORB1301030-10,BYT-ORB1301030-25,BYT-ORB1301030-50,BYT-ORB1301030-100
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Inhibitor, MAP2K, MAPKK, MEK, MEK1, MEK2, PD 318088, PD318088, PD-318088, Mitogen-activated protein kinase kinase, inhibit

Product Description

PD318088 is a non-ATP competitive, allosteric inhibitor of MEK1/2. It binds to a site adjacent to the ATP-binding pocket, allowing simultaneous occupancy with ATP. This compound is a valuable research tool for investigating the MAPK/ERK pathway in both cellular and animal models of cancer and proliferative diseases.

Product Properties

• Molecular Weight: 561.09
• Purity: 99.81% (May vary between batches)
• CAS Number: [391210-00-7]
• Formula: C16H13BrF3IN2O4
• Target: MEK

Application Notes

• Application Notes: Solubility: DMSO:112 mg/mL (199.61 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),Ethanol:14 mg/mL (24.95 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.13 mM)