Dorsomorphin dihydrochloride, CAS [[1219168-18-9]]

Catalog Number: BYT-ORB1301035
Article Name: Dorsomorphin dihydrochloride, CAS [[1219168-18-9]]
Biozol Catalog Number: BYT-ORB1301035
Supplier Catalog Number: orb1301035
Alternative Catalog Number: BYT-ORB1301035-2,BYT-ORB1301035-5,BYT-ORB1301035-1,BYT-ORB1301035-10,BYT-ORB1301035-25,BYT-ORB1301035-50,BYT-ORB1301035-100,BYT-ORB1301035-500
Manufacturer: Biorbyt
Category: Biochemikalien
Alternative Names: inhibit, pathway, Inhibitor, Compound C Dihydrochloride, Compound C, Compound C 2HCl, Compound C dihydrochloride, Dorsomorphin, Dorsomorphin (Compound C), Dorsomorphin Dihydrochloride, Dorsomorphin dihydrochloride, Dorsomorphin (Compound C) 2HCl, AMPK, AMP-activated protein kinase, Autophagy, ATP-competitive, BML 275, BML 275 Dihydrochloride, BML275, BML-275, BML-275 2HCl, BML275 Dihydrochloride, BML-275 Dihydrochloride, BML-275 dihydrochloride, BMP, receptors, Smad, type, Transforming growth factor beta receptors, TGF-b/Smad, TGFb, TGFbeta/Smad, TGF-beta, TGFbeta, TGFbeta, TGF-beta Receptor, TGF-beta/Smad
Dorsomorphin dihydrochloride (BML-275 2HCl) is a selective, ATP-competitive AMPK inhibitor (Ki=109 nM) that also blocks BMP receptors ALK2, ALK3, and ALK6. This compound induces autophagy and exhibits antitumor activity, making it a valuable tool for studying metabolic signaling, bone morphogenesis, and cancer biology in both cellular and animal models.
Molecular Weight: 472.41
Purity: 99.89% (May vary between batches)
CAS Number: [1219168-18-9]
Formula: C24H25N5O2HCl
Target: AMPK,Autophagy,TGF-beta/Smad
Application Notes: Solubility: DMSO:7.4 mg/mL (15.66 mM),H2O:47.2 mg/mL (99.91 mM)