Pralatrexate, CAS [[146464-95-1]]

Catalog Number: BYT-ORB1301055
Article Name: Pralatrexate, CAS [[146464-95-1]]
Biozol Catalog Number: BYT-ORB1301055
Supplier Catalog Number: orb1301055
Alternative Catalog Number: BYT-ORB1301055-1,BYT-ORB1301055-2,BYT-ORB1301055-5,BYT-ORB1301055-10,BYT-ORB1301055-25,BYT-ORB1301055-50,BYT-ORB1301055-100,BYT-ORB1301055-200
Manufacturer: Biorbyt
Category: Biochemikalien
Alternative Names: folylpolyglutamate, Folotyn, Inhibitor, inhibit, p27, cytotoxicity, dihydrofolate, DHFR, Antifolate, antitumor, Apoptosis, AXL, 10-Propargyl-10-deazaaminopterin, synthetase, TAM Receptor, TAMReceptor, RFC-1, reductase, Pralatrexate
Pralatrexate is a 10-deazaaminopterin analog and potent dihydrofolate reductase (DHFR) inhibitor with high affinity for the reduced folate carrier (RFC-1). It is used in research for its antineoplastic properties, applied in studies of T-cell lymphomas both in vitro and in preclinical in vivo models.
Molecular Weight: 477.47
Purity: 99.59% (May vary between batches)
CAS Number: [146464-95-1]
Formula: C23H23N7O5
Target: TAM Receptor,DHFR,Apoptosis,Antifolate
Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.19 mM),DMSO:250 mg/mL (523.59 mM),Ethanol:< 1 mg/mL (insoluble or slightly soluble),H2O:< 1 mg/mL (insoluble or slightly soluble)