USP14, Inhibitor, inhibit, IU 1, IU1, IU-1, Autophagy, DUBs, Deubiquitinase
IU1 is a cell-permeable, reversible, and specific inhibitor of the human deubiquitinase USP14, with a reported IC50 of 4.7 µM. It is a valuable research tool for studying proteasome function, protein turnover, and neurodegenerative disease mechanisms in both cellular and biochemical assays.