HIF-2alpha-IN-4, CAS [[882268-69-1]]

Catalog Number: BYT-ORB1302183
Article Name: HIF-2alpha-IN-4, CAS [[882268-69-1]]
Biozol Catalog Number: BYT-ORB1302183
Supplier Catalog Number: orb1302183
Alternative Catalog Number: BYT-ORB1302183-5, BYT-ORB1302183-1, BYT-ORB1302183-10, BYT-ORB1302183-25, BYT-ORB1302183-50, BYT-ORB1302183-100, BYT-ORB1302183-200
Manufacturer: Biorbyt
Category: Biochemikalien
Alternative Names: iron-responsive, inhibit, oxygen sensing, HIF, HIF 2alpha IN 4, HIF ProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF/HIF ProlylHydroxylase, HIF/HIF Prolyl-Hydroxylase, HIF/HIFProlylHydroxylase, HIF-2a-IN-4, HIF-2alpha, HIF2alphaIN4, HIF-2alpha-IN-4, HIF-2alpha-IN-4, HIF-PH, HIFProlylHydroxylase, HIFs, Inhibitor, hypoxia, Hypoxia-inducible factors, translation
HIF-2alpha-IN-4 is a potent small molecule inhibitor of HIF-2alpha protein synthesis, with an IC50 of 5 µM, targeting the 5UTR iron response element for oxygen sensing. It effectively suppresses both constitutive and hypoxia-induced HIF-2alpha expression, making it a valuable tool for studying HIF-2alpha biology in cancer and renal disease models in vitro.
Molecular Weight: 287.32
Purity: 98% (May vary between batches)
CAS Number: [882268-69-1]
Formula: C9H9N3O4S2
Target: HIF/HIF Prolyl-Hydroxylase
Application Notes: Solubility: DMSO:16.67 mg/mL (58.02 mM)