HIF-2alpha-IN-4 is a potent small molecule inhibitor of HIF-2alpha protein synthesis, with an IC50 of 5 µM, targeting the 5UTR iron response element for oxygen sensing. It effectively suppresses both constitutive and hypoxia-induced HIF-2alpha expression, making it a valuable tool for studying HIF-2alpha biology in cancer and renal disease models in vitro.
Molecular Weight:
287.32
Purity:
98% (May vary between batches)
CAS Number:
[882268-69-1]
Formula:
C9H9N3O4S2
Target:
HIF/HIF Prolyl-Hydroxylase
Application Notes:
Solubility: DMSO:16.67 mg/mL (58.02 mM)
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