Thiocolchicine, CAS [[2730-71-4]]

Product Overview

• Article Name: Thiocolchicine, CAS [[2730-71-4]]
• Biozol Catalog Number: BYT-ORB1303136
• Supplier Catalog Number: orb1303136
• Alternative Catalog Number: BYT-ORB1303136-1, BYT-ORB1303136-10, BYT-ORB1303136-100, BYT-ORB1303136-25, BYT-ORB1303136-5, BYT-ORB1303136-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Tubulin polymerization, Thiocolchicine, Inhibitor, MDR-positive, MCF-7, leukemia, inhibit, LoVo, LoVo/DX, Microtubule/Tubulin, Microtubule Associated, MicrotubuleAssociated, Apoptosis, Analogue, cancer, BALB/3T3, A-549, breast, Colchicine

Product Description

Thiocolchicine is a potent tubulin polymerization inhibitor (IC50=2.5 µM, Ki=0.7 µM) that induces apoptotic cell death. It serves as a cytotoxic payload in Antibody-Drug Conjugate (ADC) development and is used in cancer research for both in vitro mechanistic studies and in vivo efficacy models.

Product Properties

• Molecular Weight: 415.5
• Purity: 98.19% (May vary between batches)
• CAS Number: [2730-71-4]
• Formula: C22H25NO5S
• Target: Microtubule Associated,Apoptosis

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.94 mM),DMSO:95 mg/mL (228.64 mM)