AFN-1252 (Debio 1452) is a potent FabI enoyl-ACP reductase inhibitor active against clinical isolates of Staphylococcus aureus and S. epidermidis (MIC 0.12 µg/ml). It serves as a valuable research tool for studying bacterial fatty acid biosynthesis and has demonstrated efficacy in preclinical models of staphylococcal infection.
Molecular Weight:
375.42
Purity:
99.81% (May vary between batches)
CAS Number:
[620175-39-5]
Formula:
C22H21N3O3
Target:
Antibacterial,Antibiotic
Application Notes:
Solubility: DMSO:5.8 mg/mL (15.45 mM)
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