CAY10602, CAS [[374922-43-7]]

Product Overview

• Article Name: CAY10602, CAS [[374922-43-7]]
• Biozol Catalog Number: BYT-ORB1303213
• Supplier Catalog Number: orb1303213
• Alternative Catalog Number: BYT-ORB1303213-1, BYT-ORB1303213-10, BYT-ORB1303213-100, BYT-ORB1303213-25, BYT-ORB1303213-5, BYT-ORB1303213-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: inhibit, Inhibitor, CAY10602, CAY-10602, CAY 10602, Sirtuin, SIRT1

Product Description

CAY10602 is a potent and selective SIRT1 activator identified via high-throughput screening. It dose-dependently inhibits NF-kappaB signaling and TNF-alpha production, as demonstrated in LPS-stimulated THP-1 cell assays with ~75% inhibition at 60 µM. This compound is a valuable research tool for studying SIRT1s role in inflammation, aging, and metabolic pathways in vitro.

Product Properties

• Molecular Weight: 418.44
• Purity: >99.99% (May vary between batches)
• CAS Number: [374922-43-7]
• Formula: C22H15FN4O2S
• Target: Sirtuin

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.78 mM),DMSO:41.8 mg/mL (99.89 mM)