NH-3, CAS [[447415-26-1]]

Product Overview

• Article Name: NH-3, CAS [[447415-26-1]]
• Biozol Catalog Number: BYT-ORB1303228
• Supplier Catalog Number: orb1303228
• Alternative Catalog Number: BYT-ORB1303228-1, BYT-ORB1303228-1, BYT-ORB1303228-10, BYT-ORB1303228-100, BYT-ORB1303228-25, BYT-ORB1303228-5, BYT-ORB1303228-50, BYT-ORB1303228-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: cofactor, inhibit, Inhibitor, NH3, NH-3, NH 3, orally, GC-1, Thyroidhormonereceptor(THR), Thyroidhormonereceptor, Thyroid hormone receptor(THR), Thyroid hormone receptor, Thyroid Hormone Receptor, Thyroid hormone, thyromi-metic, THR, recruitment

Product Description

NH-3 is a potent, orally bioavailable thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM. Derived from GC-1, it reversibly blocks hormone binding and cofactor recruitment, making it a valuable tool for studying hyperthyroidism and metabolic disorders in both cellular and animal models.

Product Properties

• Molecular Weight: 473.52
• Purity: 99.40% (May vary between batches)
• CAS Number: [447415-26-1]
• Formula: C28H27NO6
• Target: Thyroid hormone receptor(THR)

Application Notes

• Application Notes: Solubility: DMSO:95 mg/mL (200.63 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.97 mM)