ML213 (CID-3111211) is a potent and selective activator of Kv7.2/KCNQ2 and Kv7.4/KCNQ4 potassium channels, with EC50 values of 230 nM and 510 nM, respectively. This small molecule is a valuable research tool for investigating channel function in neuronal excitability and hearing, supporting both in vitro electrophysiology and in vivo disease model studies.