UNC3866 TFA is a potent and selective CBX7 chromodomain antagonist, effectively disrupting its interaction with histone H3K27me3 as validated by AlphaScreen. This compound is a valuable chemical probe for studying Polycomb repression in cancer epigenetics and stem cell biology, applicable in both in vitro and cellular assays.
Molecular Weight:
909.04
Purity:
98.60% (May vary between batches)
CAS Number:
[1872382-48-3]
Formula:
C45H67F3N6O10
Target:
Histone Methyltransferase
Application Notes:
Solubility: DMSO:30 mg/mL (33 mM)
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