Cambinol, CAS [[14513-15-6]]

Product Overview

• Article Name: Cambinol, CAS [[14513-15-6]]
• Biozol Catalog Number: BYT-ORB1303297
• Supplier Catalog Number: orb1303297
• Alternative Catalog Number: BYT-ORB1303297-1, BYT-ORB1303297-1, BYT-ORB1303297-10, BYT-ORB1303297-100, BYT-ORB1303297-2, BYT-ORB1303297-25, BYT-ORB1303297-5, BYT-ORB1303297-50, BYT-ORB1303297-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Cambinol, Apoptosis, NSC112546, NSC-112546, Inhibitor, inhibit, NSC 112546, SIRT2, SIRT1, SIRT1/2 Inhibitor IV, Sirtuin, Phospholipase

Product Description

Cambinol is a cell-permeable SIRT1 and SIRT2 inhibitor with substrate-competitive activity, also functioning as a brain-penetrant neutral sphingomyelinase (N-SMase) inhibitor. It induces apoptosis in BCL6-expressing lymphoma cells via p53 and BCL6 hyperacetylation and is used in oncology and neurology research, including in vivo studies on exosome biology and cancer models.

Product Properties

• Molecular Weight: 360.43
• Purity: 99.83% (May vary between batches)
• CAS Number: [14513-15-6]
• Formula: C21H16N2O2S
• Target: Apoptosis,Sirtuin,Phospholipase

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.55 mM),Ethanol:5 mg/mL (13.87 mM),DMSO:36 mg/mL (99.88 mM)